InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP6V1G1

Summary

InnateDB Protein

IDBP-82262.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V1G1

Protein Name

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1

Synonyms

ATP6G; ATP6G1; ATP6GL; ATP6J; Vma10;

Species

Homo sapiens

Ensembl Protein

ENSP00000363162

InnateDB Gene

IDBG-82260 (ATP6V1G1)

Protein Structure

UniProt Annotation

Function

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitous. {ECO:0000269PubMed:12384298}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0051117	ATPase binding

Biological Process

GO:0006879	cellular iron ion homeostasis
GO:0008286	insulin receptor signaling pathway
GO:0015992	proton transport
GO:0033572	transferrin transport
GO:0051701	interaction with host
GO:0055085	transmembrane transport
GO:0090382	phagosome maturation

Cellular Component

GO:0005765	lysosomal membrane
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0070062	extracellular vesicular exosome