Homo sapiens Protein: WDFY1
Summary
InnateDB Protein IDBP-82284.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDFY1
Protein Name WD repeat and FYVE domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000233055
InnateDB Gene IDBG-82282 (WDFY1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Early endosome {ECO:0000269PubMed:11739631}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005545 1-phosphatidylinositol binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000306 FYVE zinc finger
IPR001680 WD40 repeat
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF01363
PF00400
PRINTS PR00320
PIRSF
SMART SM00064
SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IWB7
PhosphoSite PhosphoSite-Q8IWB7
TrEMBL A0A024R488
UniProt Splice Variant
Entrez Gene 57590
UniGene Hs.720522
RefSeq NP_065881
HUGO HGNC:20451
OMIM
CCDS CCDS33387
HPRD 15663
IMGT
EMBL AB037856 AC073641 AF411977 AJ310568 AK022888 BC040525 BC065934 CH471063
GenPept AAH40525 AAH65934 AAL04161 AAY14924 BAA92673 BAB14294 CAC83947 EAW70817 EAW70818