InnateDB Protein
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IDBP-8242.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NARFL
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Protein Name
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nuclear prelamin A recognition factor-like
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000251588
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InnateDB Gene
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IDBG-8238 (NARFL)
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Protein Structure
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Function |
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. {ECO:0000269PubMed:16956324, ECO:0000269PubMed:18270200}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:16956324}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003149
Iron hydrogenase, small subunit-like
IPR004108
Iron hydrogenase, large subunit, C-terminal
IPR009016
Iron hydrogenase
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PFAM |
PF02256
PF02906
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PRINTS |
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PIRSF |
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SMART |
SM00902
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H6Q4
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PhosphoSite |
PhosphoSite-Q9H6Q4
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TrEMBL |
I3L2A3
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UniProt Splice Variant |
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Entrez Gene |
64428
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UniGene |
Hs.513247
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RefSeq |
NP_071938
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HUGO |
HGNC:14179
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OMIM |
611118
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CCDS |
CCDS10425
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HPRD |
14810
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IMGT |
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EMBL |
AE006464
AK025641
AK025861
AK095675
AK223005
AY129231
BC030248
BC129940
CH471112
Z98258
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GenPept |
AAH30248
AAI29941
AAK61251
AAM98737
BAB15199
BAB15261
BAD96725
BAG53105
CAM26480
EAW85723
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