InnateDB Protein
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IDBP-83003.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC35G1
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Protein Name
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solute carrier family 35, member G1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000360462
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InnateDB Gene
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IDBG-83001 (SLC35G1)
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Protein Structure
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Function |
May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell. {ECO:0000269PubMed:22084111}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:22084111}; Multi-pass membrane protein {ECO:0000269PubMed:22084111}. Endoplasmic reticulum membrane {ECO:0000269PubMed:22084111}; Multi-pass membrane protein {ECO:0000269PubMed:22084111}. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed. {ECO:0000269PubMed:22084111}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000620
Drug/metabolite transporter
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PFAM |
PF00892
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q2M3R5
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PhosphoSite |
PhosphoSite-Q2M3R5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
159371
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UniGene |
Hs.743571
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RefSeq |
NP_694958
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HUGO |
HGNC:26607
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OMIM |
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CCDS |
CCDS7432
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HPRD |
15531
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IMGT |
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EMBL |
AK091309
AL138923
BC041432
BC104814
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GenPept |
AAH41432
AAI04815
BAC03633
CAH73399
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