Version 5.4
Homo sapiens Protein: PTMA
Summary
InnateDB Protein IDBP-83129.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTMA
Protein Name prothymosin, alpha
Synonyms TMSA;
Species Homo sapiens
Ensembl Protein ENSP00000344547
InnateDB Gene IDBG-83127 (PTMA)
Protein Structure
UniProt Annotation
Function Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
Experimentally validated
Total 72 [view]
Protein-Protein 67 [view]
Protein-DNA 0
Protein-RNA 4 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004931 Prothymosin/parathymosin
PFAM PF03247
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P06454
PhosphoSite PhosphoSite-P06454
TrEMBL
UniProt Splice Variant
Entrez Gene 728026
UniGene Hs.464163
RefSeq NP_001092755
HUGO HGNC:9623
OMIM 188390
CCDS CCDS42833
HPRD 01778
IMGT
EMBL AF348514 BC051265 BC066905 BC070480 BC071647 BC071879 J04797 M14483 M14630 M26708 M67480 S56449
GenPept AAA60213 AAA61182 AAA61183 AAA63239 AAA63240 AAD13882 AAH51265 AAH66905 AAH70480 AAH71647 AAH71879 AAK30146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca