Version 5.4
Homo sapiens Protein: DOCK11
Summary
InnateDB Protein IDBP-83266.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOCK11
Protein Name dedicator of cytokinesis 11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000276204
InnateDB Gene IDBG-83262 (DOCK11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001849 Pleckstrin homology domain
IPR010703 Dedicator of cytokinesis C-terminal
IPR021816 Dedicator of cytokinesis C/D, N-terminal
PFAM PF00169
PF06920
PF11878
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6NIW2
UniProt Splice Variant
Entrez Gene 139818
UniGene Hs.368203
RefSeq
HUGO HGNC:23483
OMIM 300681
CCDS
HPRD 06492
IMGT
EMBL AC007021 AL391237 AL391280
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca