Version 5.4
Homo sapiens Protein: EDN3
Summary
InnateDB Protein IDBP-83426.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EDN3
Protein Name endothelin 3
Synonyms ET-3; ET3; HSCR4; PPET3; WS4B;
Species Homo sapiens
Ensembl Protein ENSP00000360064
InnateDB Gene IDBG-83422 (EDN3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0019229 regulation of vasoconstriction
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001928 Endothelin-like toxin
IPR020475 Bibrotoxin/Sarafotoxin-D
PFAM PF00322
PRINTS PR00365
PIRSF
SMART SM00272
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6LDQ8
UniProt Splice Variant
Entrez Gene 1908
UniGene Hs.616845
RefSeq
HUGO HGNC:3178
OMIM 131242
CCDS
HPRD 00570
IMGT
EMBL AL035250 DQ096281 M25551
GenPept AAA52341 AAZ03610

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca