Version 5.4
Homo sapiens Protein: CXCR7
Summary
InnateDB Protein IDBP-84148.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CXCR7
Protein Name chemokine (C-X-C motif) receptor 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000272928
InnateDB Gene IDBG-84146 (CXCR7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0015026 coreceptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019958 C-X-C chemokine binding
Biological Process
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0006935 chemotaxis
GO:0007155 cell adhesion
GO:0007186 G-protein coupled receptor signaling pathway
GO:0016032 viral process
GO:0031623 receptor internalization
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
GO:0055037 recycling endosome
Protein Structure and Domains
PDB ID
InterPro IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001416 CXC chemokine receptor 7
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00241
PR00237
PR00646
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P25106
PhosphoSite PhosphoSite-P25106
TrEMBL
UniProt Splice Variant
Entrez Gene 57007
UniGene
RefSeq NP_064707
HUGO HGNC:23692
OMIM 610376
CCDS CCDS2516
HPRD 09882
IMGT
EMBL AC079611 AF030297 AK291659 BC036661 CH471063 DQ822477 M64749 U67784 U73141
GenPept AAA62370 AAB16913 AAB18130 AAB94130 AAH36661 AAX93086 ABH01258 BAF84348 EAW71092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca