InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RHOXF1

Summary

InnateDB Protein

IDBP-84277.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHOXF1

Protein Name

Rhox homeobox family, member 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000217999

InnateDB Gene

IDBG-84275 (RHOXF1)

Protein Structure

UniProt Annotation

Function

May be a transcription factor involved in reproductive processes.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108, ECO:0000269PubMed:11980563}.

Disease Associations

Tissue Specificity

Ovary, testis and epididymis. Also detected in the prostate and the mammary gland. Expressed in many tumor cell lines derived from acute lymphocytic leukemia, prostate, endometrial adenocarcinoma, melanoma, bladder carcinoma, colon carcinoma, erythroleukemia and breast carcinoma. Not expressed in placenta. {ECO:0000269PubMed:12490318}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0007276	gamete generation
GO:0019953	sexual reproduction
GO:0030518	intracellular steroid hormone receptor signaling pathway