InnateDB Protein
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IDBP-84375.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ADRM1
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Protein Name
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adhesion regulating molecule 1
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Synonyms
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ARM-1; ARM1; GP110;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000253003
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InnateDB Gene
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IDBG-84373 (ADRM1)
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Protein Structure
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Function |
Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. {ECO:0000269PubMed:16815440, ECO:0000269PubMed:16906146, ECO:0000269PubMed:16990800, ECO:0000269PubMed:17139257, ECO:0000269PubMed:18497817}.
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Subcellular Localization |
Cytoplasm. Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
69
[view]
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Protein-Protein |
69
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
GO:0006368
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transcription elongation from RNA polymerase II promoter
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GO:0010950
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positive regulation of endopeptidase activity
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GO:0043248
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proteasome assembly
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Cellular Component |
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PDB ID |
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InterPro |
IPR006773
26S proteasome complex ubiquitin receptor, subunit Rpn13
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PFAM |
PF04683
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q16186
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PhosphoSite |
PhosphoSite-Q16186
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
11047
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UniGene |
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RefSeq |
NP_783163
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HUGO |
HGNC:15759
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OMIM |
610650
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CCDS |
CCDS13496
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HPRD |
06440
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IMGT |
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EMBL |
AL354836
BC010733
BC017245
BR000321
D64154
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GenPept |
AAH10733
AAH17245
BAA11023
CAC22308
FAA00246
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