Homo sapiens Protein: ADRM1
Summary
InnateDB Protein IDBP-84375.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADRM1
Protein Name adhesion regulating molecule 1
Synonyms ARM-1; ARM1; GP110;
Species Homo sapiens
Ensembl Protein ENSP00000253003
InnateDB Gene IDBG-84373 (ADRM1)
Protein Structure
UniProt Annotation
Function Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. {ECO:0000269PubMed:16815440, ECO:0000269PubMed:16906146, ECO:0000269PubMed:16990800, ECO:0000269PubMed:17139257, ECO:0000269PubMed:18497817}.
Subcellular Localization Cytoplasm. Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 69 [view]
Protein-Protein 69 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0005515 protein binding
GO:0061133 endopeptidase activator activity
GO:0070628 proteasome binding
Biological Process
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010950 positive regulation of endopeptidase activity
GO:0043248 proteasome assembly
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR006773 26S proteasome complex ubiquitin receptor, subunit Rpn13
PFAM PF04683
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16186
PhosphoSite PhosphoSite-Q16186
TrEMBL
UniProt Splice Variant
Entrez Gene 11047
UniGene
RefSeq NP_783163
HUGO HGNC:15759
OMIM 610650
CCDS CCDS13496
HPRD 06440
IMGT
EMBL AL354836 BC010733 BC017245 BR000321 D64154
GenPept AAH10733 AAH17245 BAA11023 CAC22308 FAA00246