Version 5.4
Homo sapiens Protein: TUBGCP4
Summary
InnateDB Protein IDBP-8440.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBGCP4
Protein Name tubulin, gamma complex associated protein 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000260383
InnateDB Gene IDBG-8438 (TUBGCP4)
Protein Structure
UniProt Annotation
Function Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Disease Associations
Tissue Specificity Ubiquitously expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
Experimentally validated
Total 73 [view]
Protein-Protein 73 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005200 structural constituent of cytoskeleton
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0006461 protein complex assembly
GO:0007020 microtubule nucleation
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005874 microtubule
GO:0008274 gamma-tubulin ring complex
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR007259 Gamma-tubulin complex component protein
PFAM PF04130
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UGJ1
PhosphoSite PhosphoSite-Q9UGJ1
TrEMBL
UniProt Splice Variant
Entrez Gene 27229
UniGene Hs.627712
RefSeq NP_001273343
HUGO HGNC:16691
OMIM 609610
CCDS CCDS66745
HPRD 10616
IMGT
EMBL AC018924 AJ249677 AK001639 AK027703 BC009870 BC012801 CH471125
GenPept AAH09870 AAH12801 BAA91802 BAG51368 CAB62539 EAW92603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca