Version 5.4
Homo sapiens Protein: PPP1R7
Summary
InnateDB Protein IDBP-85047.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R7
Protein Name protein phosphatase 1, regulatory subunit 7
Synonyms SDS22;
Species Homo sapiens
Ensembl Protein ENSP00000272983
InnateDB Gene IDBG-85045 (PPP1R7)
Protein Structure
UniProt Annotation
Function Regulatory subunit of protein phosphatase 1. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:7498485}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008599 protein phosphatase type 1 regulator activity
GO:0030234 enzyme regulator activity
Biological Process
GO:0008150 biological_process
GO:0035307 positive regulation of protein dephosphorylation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003603 U2A\'/phosphoprotein 32 family A, C-terminal
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
SM00446
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15435
PhosphoSite PhosphoSite-Q15435
TrEMBL
UniProt Splice Variant
Entrez Gene 5510
UniGene Hs.36587
RefSeq NP_001269338
HUGO HGNC:9295
OMIM 602877
CCDS CCDS63194
HPRD 04192
IMGT
EMBL AF067130 AF067131 AF067132 AF067133 AF067134 AF067135 AF067136 AK294043 BC000910 BC012397 BC013001 BT007296 BT020134 CH471063 Z50749
GenPept AAD26610 AAD26611 AAD26612 AAD26613 AAH00910 AAH12397 AAH13001 AAP35960 AAV38936 BAG57395 CAA90626 EAW71243

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca