InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HDLBP

Summary

InnateDB Protein

IDBP-85087.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HDLBP

Protein Name

high density lipoprotein binding protein

Synonyms

HBP; PRO2900; VGL;

Species

Homo sapiens

Ensembl Protein

ENSP00000312042

InnateDB Gene

IDBG-85085 (HDLBP)

Protein Structure

UniProt Annotation

Function

Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:8605996}. Nucleus {ECO:0000269PubMed:8605996}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.

Experimentally validated
Total	56 [view]
Protein-Protein	56 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006869	lipid transport
GO:0008203	cholesterol metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0034364	high-density lipoprotein particle

Protein Structure and Domains

PDB ID

InterPro

IPR004087 K Homology domain
IPR004088 K Homology domain, type 1

PFAM

PF00013
PF13014

PRINTS

PIRSF

SMART

SM00322

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q00341

PhosphoSite

PhosphoSite-Q00341

TrEMBL

Q96CF6

UniProt Splice Variant

Entrez Gene

3069

UniGene

Hs.613864

RefSeq

NP_005327

HUGO

HGNC:4857

OMIM

142695

CCDS

CCDS2547

HPRD

00813

IMGT

EMBL

AC104841 AK300312 BC001179 BC014305 CH471063 M64098

GenPept

AAA35962 AAH01179 AAH14305 AAY14717 BAG62064 EAW71253 EAW71254 EAW71255