Version 5.4
Homo sapiens Protein: CABLES2
Summary
InnateDB Protein IDBP-85118.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CABLES2
Protein Name Cdk5 and Abl enzyme substrate 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000279101
InnateDB Gene IDBG-85116 (CABLES2)
Protein Structure
UniProt Annotation
Function Unknown. Probably involved in G1-S cell cycle transition.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0007049 cell cycle
GO:0045859 regulation of protein kinase activity
GO:0051301 cell division
GO:0051302 regulation of cell division
GO:0051726 regulation of cell cycle
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006671 Cyclin, N-terminal
IPR012388 Cdk5/c-Abl linker protein Cables
IPR013763 Cyclin-like
PFAM PF00134
PRINTS
PIRSF PIRSF025798
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BTV7
PhosphoSite PhosphoSite-Q9BTV7
TrEMBL
UniProt Splice Variant
Entrez Gene 81928
UniGene Hs.301040
RefSeq NP_112492
HUGO HGNC:16143
OMIM
CCDS CCDS33503
HPRD 12994
IMGT
EMBL AL121832 BC003122
GenPept AAH03122 CAI23283

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca