Version 5.4
Homo sapiens Protein: FAM125B
Summary
InnateDB Protein IDBP-85417.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM125B
Protein Name family with sequence similarity 125, member B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354772
InnateDB Gene IDBG-85413 (FAM125B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0015031 protein transport
GO:0042058 regulation of epidermal growth factor receptor signaling pathway
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Cellular Component
GO:0000813 ESCRT I complex
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0031902 late endosome membrane
GO:0031982 vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR018798 FAM125
PFAM PF10240
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H7P6
PhosphoSite PhosphoSite-Q9H7P6
TrEMBL Q9H7N7
UniProt Splice Variant
Entrez Gene 89853
UniGene Hs.623619
RefSeq NP_258257
HUGO HGNC:23368
OMIM
CCDS CCDS35142
HPRD 12952
IMGT
EMBL AK024432 AK024441 BC028675 CH471090
GenPept AAH28675 BAB15722 BAB15731 EAW87639 EAW87640

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca