InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FTSJD2

Summary

InnateDB Protein

IDBP-85638.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FTSJD2

Protein Name

FtsJ methyltransferase domain containing 2

Synonyms

FTSJD2; hMTr1; KIAA0082; MTr1;

Species

Homo sapiens

Ensembl Protein

ENSP00000362550

InnateDB Gene

IDBG-85636 (FTSJD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
GO:0005515	protein binding
GO:0008168	methyltransferase activity

Biological Process

GO:0006370	7-methylguanosine mRNA capping
GO:0032259	methylation
GO:0080009	mRNA methylation
GO:0097309	cap1 mRNA methylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000467 G-patch domain
IPR001202 WW domain
IPR002877 Ribosomal RNA methyltransferase FtsJ domain
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01585
PF00397
PF01728

PRINTS

PIRSF

SMART

SM00443
SM00456

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8N1G2