Version 5.4
Homo sapiens Protein: ENTPD7
Summary
InnateDB Protein IDBP-86090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENTPD7
Protein Name ectonucleoside triphosphate diphosphohydrolase 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359520
InnateDB Gene IDBG-86088 (ENTPD7)
Protein Structure
UniProt Annotation
Function Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes to intracellular vesicular compartments. {ECO:0000269PubMed:11278936}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR000407 Nucleoside phosphatase GDA1/CD39
PFAM PF01150
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQZ7
PhosphoSite PhosphoSite-Q9NQZ7
TrEMBL
UniProt Splice Variant
Entrez Gene 57089
UniGene Hs.740488
RefSeq NP_065087
HUGO HGNC:19745
OMIM
CCDS CCDS7480
HPRD 10939
IMGT
EMBL AF269255 AK055540 AK314542 AL133353 BC119008 BC122857 CH471066
GenPept AAF90135 AAI19009 AAI22858 BAG37130 BAG51533 CAI14498 EAW49861

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca