Version 5.4
Homo sapiens Protein: SLC25A14
Summary
InnateDB Protein IDBP-86102.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A14
Protein Name solute carrier family 25 (mitochondrial carrier, brain), member 14
Synonyms BMCP1; UCP5;
Species Homo sapiens
Ensembl Protein ENSP00000342797
InnateDB Gene IDBG-86094 (SLC25A14)
Protein Structure
UniProt Annotation
Function Participates in the mitochondrial proton leak measured in brain mitochondria.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Mainly expressed in brain. Some expression in testis and pituitary. {ECO:0000269PubMed:10928996}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0006839 mitochondrial transport
GO:0009060 aerobic respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR002067 Mitochondrial carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS PR00926
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95258
PhosphoSite PhosphoSite-O95258
TrEMBL
UniProt Splice Variant
Entrez Gene 9016
UniGene Hs.743000
RefSeq
HUGO HGNC:10984
OMIM 300242
CCDS CCDS76020
HPRD 02214
IMGT
EMBL AF078544 AF155809 AF155810 AF155811 AL035423 AY358099 BC119666 BC119667 CH471107
GenPept AAD04346 AAG29582 AAG29583 AAG29584 AAI19667 AAI19668 AAQ88466 CAB41251 CAI42440 CAI42441 EAX11804

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca