Version 5.4
Homo sapiens Protein: ARHGAP36
Summary
InnateDB Protein IDBP-86316.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP36
Protein Name Rho GTPase activating protein 36
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359960
InnateDB Gene IDBG-86312 (ARHGAP36)
Protein Structure
UniProt Annotation
Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PRINTS
PIRSF
SMART SM00324
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZRI8
PhosphoSite PhosphoSite-Q6ZRI8
TrEMBL X6RIA0
UniProt Splice Variant
Entrez Gene 158763
UniGene Hs.22905
RefSeq NP_001269536
HUGO HGNC:26388
OMIM
CCDS CCDS65320
HPRD 06547
IMGT
EMBL AK054620 AK128203 AK294274 AK296748 AL590131 BC063790 CH471107
GenPept AAH63790 BAB70776 BAC87322 BAH11720 BAH12425 CAI41398 CAI41399 CAI41400 CAI41401 EAX11793

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca