Version 5.4
Homo sapiens Protein: TSPO2
Summary
InnateDB Protein IDBP-86459.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPO2
Protein Name translocator protein 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362255
InnateDB Gene IDBG-86457 (TSPO2)
Protein Structure
UniProt Annotation
Function Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation. {ECO:0000269PubMed:19729679}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:19729679}; Multi-pass membrane protein {ECO:0000269PubMed:19729679}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015485 cholesterol binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004307 TspO/MBR-related protein
PFAM PF03073
PRINTS
PIRSF PIRSF005859
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5TGU0
PhosphoSite PhosphoSite-Q5TGU0
TrEMBL
UniProt Splice Variant
Entrez Gene 222642
UniGene Hs.357392
RefSeq NP_001010873
HUGO HGNC:21256
OMIM
CCDS CCDS34444
HPRD 16569
IMGT
EMBL AL031778 BC104440 BC104441 BC137560 BC137565 BC144710
GenPept AAI04441 AAI04442 AAI37561 AAI37566 AAI44711 CAB44739

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca