InnateDB Protein
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IDBP-86577.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NDUFB8
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Protein Name
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NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000299166
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InnateDB Gene
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IDBG-86575 (NDUFB8)
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Protein Structure
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Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Subcellular Localization |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
17
[view]
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Protein-Protein |
17
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003954
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NADH dehydrogenase activity
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GO:0008137
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NADH dehydrogenase (ubiquinone) activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008699
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
IPR016551
NADH:ubiquinone oxidoreductase, beta subcomplex, subunit 8
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PFAM |
PF05821
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PRINTS |
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PIRSF |
PIRSF009288
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O95169
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PhosphoSite |
PhosphoSite-O95169
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TrEMBL |
E9PIZ8
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UniProt Splice Variant |
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Entrez Gene |
4714
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UniGene |
Hs.523215
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RefSeq |
NP_004995
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HUGO |
HGNC:7703
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OMIM |
602140
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CCDS |
CCDS7497
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HPRD |
11886
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IMGT |
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EMBL |
AF044958
AF077028
AF115968
AK289579
AK295867
AL080056
AL133352
BC000466
BC019276
BI602529
CH471066
CR533490
Y18944
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GenPept |
AAD05422
AAD27761
AAH00466
AAH19276
AAP97239
BAF82268
BAG58666
CAB45691
CAB46274
CAG38521
CAH73563
EAW49819
EAW49820
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