Version 5.4
Homo sapiens Protein: USP26
Summary
InnateDB Protein IDBP-86681.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP26
Protein Name ubiquitin specific peptidase 26
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359869
InnateDB Gene IDBG-86679 (USP26)
Protein Structure
UniProt Annotation
Function Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity). Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway. {ECO:0000250, ECO:0000269PubMed:20501646}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20501646}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
PFAM PF00443
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXU7
PhosphoSite PhosphoSite-Q9BXU7
TrEMBL
UniProt Splice Variant
Entrez Gene 83844
UniGene Hs.731249
RefSeq NP_114113
HUGO HGNC:13485
OMIM 300309
CCDS CCDS14635
HPRD 02255
IMGT
EMBL AF285593 BC069073 BC101190 BC101191 Z81365
GenPept AAH69073 AAI01191 AAI01192 AAK31972 CAX30813

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca