Version 5.4
Homo sapiens Protein: FAM178A
Summary
InnateDB Protein IDBP-86721.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM178A
Protein Name family with sequence similarity 178, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000238961
InnateDB Gene IDBG-86719 (FAM178A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000269PubMed:24561620}. Note=Mainly localizes to nucleus: colocalizes with PCNA on replication sites.
Disease Associations
Tissue Specificity Widely expressed. Expressed at higher level in skeletal muscle and at slightly lower level in brain, liver and heart, than in lung, kidney, spleen and thymus. {ECO:0000269PubMed:12459258}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0000785 chromatin
GO:0005615 extracellular space
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IX21
PhosphoSite PhosphoSite-Q8IX21
TrEMBL
UniProt Splice Variant
Entrez Gene 55719
UniGene Hs.706439
RefSeq NP_060591
HUGO HGNC:17814
OMIM 610348
CCDS CCDS7500
HPRD 12581
IMGT
EMBL AF460991 AK001374 AK292565 AL133215 AL138762 BC030565 BC073832
GenPept AAH73832 AAN84475 BAA91657 BAF85254 CAH70949 CAH70950 CAI10932 CAI10933

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca