InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RTEL1

Summary

InnateDB Protein

IDBP-86847.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RTEL1

Protein Name

Regulator of telomere elongation helicase 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000349265

InnateDB Gene

IDBG-544022 (RTEL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004003	ATP-dependent DNA helicase activity
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Biological Process

GO:0032508

DNA duplex unwinding

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR006554 Helicase-like, DEXD box c2 type
IPR006935 Helicase/UvrB domain
IPR010614 DEAD2
IPR014013 Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF04851
PF06733

PRINTS

PIRSF

SMART

SM00488

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite