Version 5.4
Homo sapiens Protein: SFXN3
Summary
InnateDB Protein IDBP-86946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFXN3
Protein Name sideroflexin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000224807
InnateDB Gene IDBG-86944 (SFXN3)
Protein Structure
UniProt Annotation
Function Potential iron transporter.
Subcellular Localization Mitochondrion membrane {ECO:0000269Ref.4}; Multi-pass membrane protein {ECO:0000269Ref.4}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0055072 iron ion homeostasis
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro IPR004686 Tricarboxylate/iron carrier
PFAM PF03820
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BWM7
PhosphoSite PhosphoSite-Q9BWM7
TrEMBL
UniProt Splice Variant
Entrez Gene 81855
UniGene Hs.283844
RefSeq NP_112233
HUGO HGNC:16087
OMIM 615571
CCDS CCDS7508
HPRD 15329
IMGT
EMBL AK074707 AL133215 BC000124
GenPept AAH00124 BAC11151 CAI10936

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca