InnateDB Protein
|
IDBP-87026.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
PIP5KL1
|
Protein Name
|
phosphatidylinositol-4-phosphate 5-kinase-like 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000373399
|
InnateDB Gene
|
IDBG-87022 (PIP5KL1)
|
Protein Structure
|
|
Function |
May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR002498
Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034
Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
|
PFAM |
PF01504
|
PRINTS |
|
PIRSF |
|
SMART |
SM00330
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q5T9C9
|
PhosphoSite |
PhosphoSite-Q5T9C9
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
138429
|
UniGene |
Hs.734928
|
RefSeq |
NP_001128691
|
HUGO |
HGNC:28711
|
OMIM |
612865
|
CCDS |
CCDS48030
|
HPRD |
15139
|
IMGT |
|
EMBL |
AL157935
BC042184
|
GenPept |
AAH42184
CAI12614
CAM14148
|
|
|