Version 5.4
Homo sapiens Protein: NAIF1
Summary
InnateDB Protein IDBP-87238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAIF1
Protein Name nuclear apoptosis inducing factor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362170
InnateDB Gene IDBG-87236 (NAIF1)
Protein Structure
UniProt Annotation
Function Induces apoptosis. {ECO:0000269PubMed:16378748}.
Subcellular Localization Nucleus {ECO:0000269PubMed:16378748, ECO:0000269PubMed:18339812}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:16378748}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0030308 negative regulation of cell growth
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q69YI7
PhosphoSite PhosphoSite-
TrEMBL A0A024R887
UniProt Splice Variant
Entrez Gene 203245
UniGene Hs.740682
RefSeq NP_931045
HUGO HGNC:25446
OMIM 610673
CCDS CCDS6889
HPRD 12987
IMGT
EMBL AK122729 AL360268 AL833392 BC021580 CH471090
GenPept AAH21580 BAG53693 CAH10588 CAH73132 EAW87735 EAW87737

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca