InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UCKL1

Summary

InnateDB Protein

IDBP-87477.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UCKL1

Protein Name

uridine-cytidine kinase 1-like 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000346155

InnateDB Gene

IDBG-87471 (UCKL1)

Protein Structure

UniProt Annotation

Function

May contribute to UTP accumulation needed for blast transformation and proliferation. {ECO:0000269PubMed:12199906}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:12199906}. Nucleus {ECO:0000269PubMed:12199906}. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.

Disease Associations

Tissue Specificity

Ubiquitous. {ECO:0000269PubMed:12199906}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004849	uridine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity

Biological Process

GO:0008152	metabolic process
GO:0016032	viral process
GO:0016310	phosphorylation
GO:0044206	UMP salvage
GO:0044211	CTP salvage

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000764 Uridine kinase like
IPR006082 Phosphoribulokinase
IPR006083 Phosphoribulokinase/uridine kinase
IPR012853 Chloramphenicol phosphotransferase-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029057 Phosphoribosyltransferase-like

PFAM

PF00485
PF07931

PRINTS

PR00988
PR00478

PIRSF

PIRSF007531

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt