InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KLHDC3

Summary

InnateDB Protein

IDBP-87612.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KLHDC3

Protein Name

kelch domain containing 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000313995

InnateDB Gene

IDBG-87610 (KLHDC3)

Protein Structure

UniProt Annotation

Function

May be involved in meiotic recombination process.

Subcellular Localization

Cytoplasm. Note=Also found in meiotic chromatin. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005515	protein binding

Biological Process

GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0007131	reciprocal meiotic recombination
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0000790	nuclear chromatin
GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR006652 Kelch repeat type 1
IPR011498 Kelch repeat type 2

PFAM

PF01344
PF07646

PRINTS

PIRSF

SMART

SM00612

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9BQ90

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

116138

UniGene

Hs.740012

RefSeq

NP_476502

HUGO

HGNC:20704

OMIM

611248

CCDS

CCDS4880

HPRD

13922

IMGT

EMBL

AB055925 AK290384 AL136304 BC000295 BC001789 BC001793 BC007296 BC021546 CH471081

GenPept

AAH00295 AAH01789 AAH01793 AAH07296 AAH21546 BAB63257 BAF83073 CAI19796 EAX04136