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InnateDB Protein
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IDBP-87813.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NOLC1
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Protein Name
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nucleolar and coiled-body phosphoprotein 1
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Synonyms
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NOPP130; NOPP140; NS5ATP13; P130;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000359024
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InnateDB Gene
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IDBG-87811 (NOLC1)
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Protein Structure
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| Function |
Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.
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| Subcellular Localization |
Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
72
[view]
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| Protein-Protein |
66
[view]
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| Protein-DNA |
5
[view]
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| Protein-RNA |
0
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| DNA-DNA |
1
[view]
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR006594
LisH dimerisation motif
IPR007718
SRP40, C-terminal
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| PFAM |
PF05022
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| PRINTS |
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| PIRSF |
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| SMART |
SM00667
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q14978
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| TrEMBL |
Q96J17
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| UniProt Splice Variant |
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| Entrez Gene |
9221
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| UniGene |
Hs.523238
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| RefSeq |
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| HUGO |
HGNC:15608
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| OMIM |
602394
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AK056755
AL500527
BC006769
CH471066
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| GenPept |
AAH06769
BAG51805
EAW49713
EAW49717
EAW49718
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Version 5.4