Version 5.4
Homo sapiens Protein: SWI5
Summary
InnateDB Protein IDBP-87874.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SWI5
Protein Name SWI5 recombination repair homolog (yeast)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000316609
InnateDB Gene IDBG-87870 (SWI5)
Protein Structure
UniProt Annotation
Function Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. {ECO:0000269PubMed:21252223}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0071479 cellular response to ionizing radiation
Cellular Component
GO:0005634 nucleus
GO:0032798 Swi5-Sfr1 complex
Protein Structure and Domains
PDB ID
InterPro IPR010760 DNA repair protein, Swi5
PFAM PF07061
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1ZZU3
PhosphoSite PhosphoSite-Q1ZZU3
TrEMBL V9GYD7
UniProt Splice Variant
Entrez Gene 375757
UniGene
RefSeq NP_001035100
HUGO HGNC:31412
OMIM
CCDS CCDS43883
HPRD
IMGT
EMBL AL590708 BC029911 DQ414820
GenPept AAH29911 ABD72916 CAI13840 CAI13843 CAI13844

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca