Version 5.4
Homo sapiens Protein: TRUB2
Summary
InnateDB Protein IDBP-87887.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRUB2
Protein Name TruB pseudouridine (psi) synthase homolog 2 (E. coli)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361982
InnateDB Gene IDBG-87885 (TRUB2)
Protein Structure
UniProt Annotation
Function May be responsible for synthesis of pseudouridine from uracil in transfer RNAs. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001522 pseudouridine synthesis
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0009451 RNA modification
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002501 Pseudouridine synthase II
IPR020103 Pseudouridine synthase, catalytic domain
PFAM PF01509
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95900
PhosphoSite PhosphoSite-O95900
TrEMBL B7Z7G5
UniProt Splice Variant
Entrez Gene 26995
UniGene Hs.717996
RefSeq NP_056494
HUGO HGNC:17170
OMIM 610727
CCDS CCDS6897
HPRD 18230
IMGT
EMBL AF131848 AK001956 AK301986 AL359091 BC001457 CH471090
GenPept AAD20059 AAH01457 BAA92001 BAH13601 CAI13485 EAW87770 EAW87773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca