Version 5.4
| Homo sapiens Protein: SLITRK2 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-88348.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | SLITRK2 | ||||
| Protein Name | SLIT and NTRK-like family, member 2 | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Protein | ENSP00000359521 | ||||
| InnateDB Gene | IDBG-88344 (SLITRK2) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Suppresses neurite outgrowth. {ECO:0000250UniProtKB:Q810C0}. | ||||
| Subcellular Localization | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. | ||||
| Disease Associations | |||||
| Tissue Specificity | Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors. {ECO:0000269PubMed:14557068}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR000372
Leucine-rich repeat-containing N-terminal IPR000483 Cysteine-rich flanking region, C-terminal IPR001611 Leucine-rich repeat IPR003591 Leucine-rich repeat, typical subtype |
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| PFAM |
PF01462
PF01463 PF00560 PF13504 PF13855 |
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| PRINTS | |||||
| PIRSF | |||||
| SMART |
SM00013
SM00082 SM00369 |
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q9H156 | ||||
| PhosphoSite | PhosphoSite-Q9H156 | ||||
| TrEMBL | B3KTY4 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 84631 | ||||
| UniGene | Hs.609675 | ||||
| RefSeq | NP_115928 | ||||
| HUGO | HGNC:13449 | ||||
| OMIM | 300561 | ||||
| CCDS | CCDS14680 | ||||
| HPRD | 06603 | ||||
| IMGT | |||||
| EMBL | AB058757 AK091015 AK096278 AK289732 AL109653 AY358828 BC113011 BC113012 CH471175 Y19205 | ||||
| GenPept | AAI13012 AAI13013 AAQ89187 BAB47483 BAC03566 BAF82421 BAG53246 CAC18888 CAC80724 CAI41645 EAW53954 | ||||