Version 5.4
Homo sapiens Protein: GPR157
Summary
InnateDB Protein IDBP-88479.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR157
Protein Name G protein-coupled receptor 157
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366628
InnateDB Gene IDBG-88477 (GPR157)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000539 Frizzled protein
IPR000832 GPCR, family 2, secretin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR017981 GPCR, family 2-like
IPR022343 GCR1-cAMP receptor
PFAM PF00001
PF01534
PF00002
PRINTS PR00237
PR00489
PR00249
PR02001
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5UAW9
PhosphoSite PhosphoSite-Q5UAW9
TrEMBL
UniProt Splice Variant
Entrez Gene 80045
UniGene Hs.594343
RefSeq NP_079256
HUGO HGNC:23687
OMIM
CCDS CCDS100
HPRD 17068
IMGT
EMBL AK022194 AL158048 AY768808
GenPept AAV35060 BAB13982 CAM12842

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca