Version 5.4
Homo sapiens Protein: SFR1
Summary
InnateDB Protein IDBP-88789.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFR1
Protein Name SWI5-dependent recombination repair 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358742
InnateDB Gene IDBG-88785 (SFR1)
Protein Structure
UniProt Annotation
Function Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. {ECO:0000269PubMed:21252223}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:21252223}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
Cellular Component
GO:0005634 nucleus
GO:0032798 Swi5-Sfr1 complex
Protein Structure and Domains
PDB ID
InterPro IPR018468 Double-strand recombination repair protein, Mei5-like
PFAM PF10376
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XK3
PhosphoSite PhosphoSite-Q86XK3
TrEMBL
UniProt Splice Variant
Entrez Gene 119392
UniGene
RefSeq NP_001002759
HUGO HGNC:29574
OMIM
CCDS CCDS31279
HPRD 12590
IMGT
EMBL AK291184 AL357336 BC020892 BC140835 CH471066
GenPept AAH20892 AAI40836 BAF83873 CAI40454 CAI40456 EAW49610 EAW49611

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca