Version 5.4
Homo sapiens Protein: PHYHD1
Summary
InnateDB Protein IDBP-88812.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHYHD1
Protein Name phytanoyl-CoA dioxygenase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000340945
InnateDB Gene IDBG-88806 (PHYHD1)
Protein Structure
UniProt Annotation
Function Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity. {ECO:0000269PubMed:21530488}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR008775 Phytanoyl-CoA dioxygenase
PFAM PF05721
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SRE7
PhosphoSite PhosphoSite-Q5SRE7
TrEMBL X6RFQ9
UniProt Splice Variant
Entrez Gene 254295
UniGene Hs.709447
RefSeq
HUGO HGNC:23396
OMIM
CCDS CCDS43886
HPRD 17850
IMGT
EMBL AK095000 AL672142 BC009373 BC051300 BC053853 CH471090
GenPept AAH09373 AAH51300 AAH53853 BAG52969 CAI10840 CAI10842 CAI10843 CAO72146 CAO72147 CAQ77683 EAW87844 EAW87845 EAW87847

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca