Version 5.4
Homo sapiens Protein: PASD1
Summary
InnateDB Protein IDBP-88909.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PASD1
Protein Name PAS domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359382
InnateDB Gene IDBG-88907 (PASD1)
Protein Structure
UniProt Annotation
Function May function as a transcription factor. {ECO:0000269PubMed:15162151}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL. {ECO:0000269PubMed:15162151}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000014 PAS domain
PFAM PF13188
PF13426
PRINTS
PIRSF
SMART SM00091
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IV76
PhosphoSite PhosphoSite-Q8IV76
TrEMBL
UniProt Splice Variant
Entrez Gene 139135
UniGene Hs.160594
RefSeq NP_775764
HUGO HGNC:20686
OMIM
CCDS CCDS35431
HPRD 06613
IMGT
EMBL AK097552 AY270020 AY623425 BC040301
GenPept AAH40301 AAQ01136 AAT49049 BAC05097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca