InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MAGEA4

Summary

InnateDB Protein

IDBP-88986.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAGEA4

Protein Name

melanoma antigen family A, 4

Synonyms

CT1.4; MAGE-41; MAGE-X2; MAGE4; MAGE4A; MAGE4B;

Species

Homo sapiens

Ensembl Protein

ENSP00000359360

InnateDB Gene

IDBG-88978 (MAGEA4)

Protein Structure

UniProt Annotation

Function

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

InterPro

IPR002190 MAGE protein
IPR021072 Melanoma associated antigen, MAGE, N-terminal

PFAM

PF01454
PF12440

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P43358

PhosphoSite

PhosphoSite-P43358

TrEMBL

C9JZJ5

UniProt Splice Variant

Entrez Gene

4103

UniGene

Hs.37107

RefSeq

XP_005274734

HUGO

HGNC:6802

OMIM

300175

CCDS

CCDS14702

HPRD

02167

IMGT

EMBL

AF274855 AK300179 BC017723 CH471169 D32075 D32077 U10340 U10687 U10688

GenPept

AAA19007 AAA68871 AAA68872 AAH17723 BAA06841 BAA06843 BAG61958 EAW99410 EAW99411 EAW99412 EAW99413