Version 5.4
Homo sapiens Protein: BTG3
Summary
InnateDB Protein IDBP-895.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTG3
Protein Name BTG family, member 3
Synonyms ANA; TOB5; TOB55; TOFA;
Species Homo sapiens
Ensembl Protein ENSP00000284879
InnateDB Gene IDBG-891 (BTG3)
Protein Structure
UniProt Annotation
Function Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. High expression in the ventricular zone of the developing central nervous system. High in ovary, testis, prostate, thymus and lung. {ECO:0000269PubMed:9067576}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0045930 negative regulation of mitotic cell cycle
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002087 Anti-proliferative protein
PFAM PF07742
PRINTS PR00310
PIRSF
SMART SM00099
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14201
PhosphoSite PhosphoSite-Q14201
TrEMBL Q9UHB2
UniProt Splice Variant
Entrez Gene 10950
UniGene Hs.473420
RefSeq NP_006797
HUGO HGNC:1132
OMIM 605674
CCDS CCDS13569
HPRD 10415
IMGT
EMBL AF200465 AK289408 AP000432 AP000967 BC011957 BT007276 CH471079 CR457061 D64110
GenPept AAF24345 AAH11957 AAP35940 BAA33788 BAF82097 CAG33342 EAX10026 EAX10027 EAX10028 EAX10029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca