Version 5.4
Homo sapiens Protein: ENPP5
Summary
InnateDB Protein IDBP-89826.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENPP5
Protein Name ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000230565
InnateDB Gene IDBG-89824 (ENPP5)
Protein Structure
UniProt Annotation
Function May play a role in neuronal cell communication. Lacks nucleotide pyrophosphatase and lysopholipase D activity (By similarity). {ECO:0000250UniProtKB:P84039}.
Subcellular Localization Secreted {ECO:0000305}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF01663
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJA9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 59084
UniGene Hs.614831
RefSeq NP_067547
HUGO HGNC:13717
OMIM
CCDS CCDS4915
HPRD 13272
IMGT
EMBL AL035701 AY358514 BC027615 CH471081
GenPept AAH27615 AAQ88878 CAB56566 EAX04293

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca