InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GPR116

Summary

InnateDB Protein

IDBP-90017.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPR116

Protein Name

G protein-coupled receptor 116

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000265417

InnateDB Gene

IDBG-90015 (GPR116)

Protein Structure

UniProt Annotation

Function

May have a role in the regulation of acid-base balance. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031410	cytoplasmic vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000082 SEA domain
IPR000203 GPS motif
IPR000832 GPCR, family 2, secretin-like
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR008078 GPCR, family 2, Ig-hepta receptor
IPR013098 Immunoglobulin I-set
IPR017981 GPCR, family 2-like

PFAM

PF01390
PF01825
PF00002
PF07679

PRINTS

PR00249
PR01695

PIRSF

SMART

SM00200
SM00303
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt