Version 5.4
| Homo sapiens Protein: CRISP2 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-90252.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | CRISP2 | ||||||
| Protein Name | cysteine-rich secretory protein 2 | ||||||
| Synonyms | CRISP-2; CT36; GAPDL5; TPX1; TSP1; | ||||||
| Species | Homo sapiens | ||||||
| Ensembl Protein | ENSP00000339155 | ||||||
| InnateDB Gene | IDBG-90250 (CRISP2) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. {ECO:0000250}. | ||||||
| Subcellular Localization | Secreted {ECO:0000305}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Testis and epididymis. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | |||||||
| InterPro |
IPR001283
Cysteine-rich secretory protein, allergen V5/Tpx-1-related IPR013871 Cysteine-rich secretory protein IPR014044 CAP domain |
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| PFAM |
PF08562
PF00188 |
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| PRINTS |
PR00837
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| PIRSF |
PIRSF038921
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| SMART |
SM00198
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | P16562 | ||||||
| PhosphoSite | PhosphoSite-P16562 | ||||||
| TrEMBL | A0A024RD74 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 7180 | ||||||
| UniGene | |||||||
| RefSeq | NP_003287 | ||||||
| HUGO | HGNC:12024 | ||||||
| OMIM | 187430 | ||||||
| CCDS | CCDS4928 | ||||||
| HPRD | 01758 | ||||||
| IMGT | |||||||
| EMBL | AK223337 AK292385 AL121950 AY289796 AY292862 AY292863 AY773479 BC022011 BC107707 CH471081 M25532 X95239 | ||||||
| GenPept | AAA61220 AAH22011 AAI07708 AAP41200 AAP44113 AAP44114 AAV48552 BAD97057 BAF85074 CAA64526 CAC10520 EAX04340 EAX04341 EAX04342 EAX04343 EAX04344 EAX04345 EAX04346 EAX04347 | ||||||