Homo sapiens Protein: CRISP3
Summary
InnateDB Protein IDBP-90276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRISP3
Protein Name cysteine-rich secretory protein 3
Synonyms Aeg2; CRISP-3; CRS3; dJ442L6.3; SGP28;
Species Homo sapiens
Ensembl Protein ENSP00000263045
InnateDB Gene IDBG-90274 (CRISP3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted. Note=In neutrophils, localized in specific granules.
Disease Associations
Tissue Specificity Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006952 defense response
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0042581 specific granule
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
IPR013871 Cysteine-rich secretory protein
IPR014044 CAP domain
PFAM PF08562
PF00188
PRINTS PR00837
PIRSF PIRSF038921
SMART SM00198
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P54108
PhosphoSite PhosphoSite-P54108
TrEMBL J3KQX0
UniProt Splice Variant
Entrez Gene 10321
UniGene Hs.404466
RefSeq NP_006052
HUGO HGNC:16904
OMIM
CCDS CCDS4929
HPRD 11788
IMGT
EMBL AK223380 AK292786 AK313387 AL121950 AL121974 BC069580 BC069602 BC101539 DB205467 X94323 X95240
GenPept AAH69580 AAH69602 AAI01540 BAD97100 BAF85475 BAG36185 CAA63984 CAA64527 CAI20517 CAI20995