Homo sapiens Protein: HCRTR2 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||
InnateDB Protein | IDBP-91154.5 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | HCRTR2 | ||||||||
Protein Name | hypocretin (orexin) receptor 2 | ||||||||
Synonyms | OX2R; | ||||||||
Species | Homo sapiens | ||||||||
Ensembl Protein | ENSP00000359899 | ||||||||
InnateDB Gene | IDBG-91152 (HCRTR2) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. | ||||||||
Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | |||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||
Gene Ontology | |||||||||
Molecular Function |
|
||||||||
Biological Process |
|
||||||||
Cellular Component |
|
||||||||
Protein Structure and Domains | |||||||||
PDB ID | |||||||||
InterPro |
IPR000204
Orexin receptor family IPR000276 G protein-coupled receptor, rhodopsin-like IPR000611 Neuropeptide Y receptor family IPR004060 Orexin receptor 2 IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx |
||||||||
PFAM |
PF00001
PF03827 PF10320 |
||||||||
PRINTS |
PR01064
PR00237 PR01012 PR01522 |
||||||||
PIRSF | |||||||||
SMART | |||||||||
TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | O43614 | ||||||||
PhosphoSite | PhosphoSite-O43614 | ||||||||
TrEMBL | S4X0W3 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 3062 | ||||||||
UniGene | Hs.151624 | ||||||||
RefSeq | NP_001517 | ||||||||
HUGO | HGNC:4849 | ||||||||
OMIM | 602393 | ||||||||
CCDS | CCDS4956 | ||||||||
HPRD | 08374 | ||||||||
IMGT | |||||||||
EMBL | AF041245 AL449104 AL591718 AY062031 CH471081 EF633107 EF633108 EF633109 EF633110 KC812499 | ||||||||
GenPept | AAC39602 AAL47215 ABR23648 ABR23649 ABR23650 ABR23651 AGP04116 CAH73407 CAI19665 EAX04440 | ||||||||