Version 5.4
Homo sapiens Protein: GFRAL
Summary
InnateDB Protein IDBP-91173.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GFRAL
Protein Name GDNF family receptor alpha like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000343636
InnateDB Gene IDBG-91171 (GFRAL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0031098 stress-activated protein kinase signaling cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR016017 GDNF/GAS1
PFAM PF02351
PRINTS
PIRSF
SMART SM00907
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UXV0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 389400
UniGene Hs.526967
RefSeq NP_997293
HUGO HGNC:32789
OMIM
CCDS CCDS4957
HPRD 15622
IMGT
EMBL AL592426 AY358198
GenPept AAQ88565 CAH72998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca