InnateDB Protein
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IDBP-91324.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PPAPDC1A
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Protein Name
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phosphatidic acid phosphatase type 2 domain containing 1A
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000358069
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InnateDB Gene
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IDBG-91322 (PPAPDC1A)
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Protein Structure
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Function |
Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. {ECO:0000269PubMed:17590538}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed mainly to the brain, kidney and testis, and to a lesser extent the bone marrow, thymus, prostate, liver and uterus. {ECO:0000269PubMed:17590538}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000326
Phosphatidic acid phosphatase type 2/haloperoxidase
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PFAM |
PF01569
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PRINTS |
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PIRSF |
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SMART |
SM00014
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q5VZY2
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TrEMBL |
X6R787
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UniProt Splice Variant |
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Entrez Gene |
196051
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UniGene |
Hs.40479
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RefSeq |
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HUGO |
HGNC:23531
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OMIM |
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CCDS |
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HPRD |
18745
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IMGT |
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EMBL |
AC023282
AC073587
AL157782
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GenPept |
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