InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RSG1

Summary

InnateDB Protein

IDBP-91456.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RSG1

Protein Name

REM2 and RAB-like small GTPase 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000364749

InnateDB Gene

IDBG-91454 (RSG1)

Protein Structure

UniProt Annotation

Function

Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005525	GTP binding

Biological Process

GO:0006887	exocytosis
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0017157	regulation of exocytosis
GO:0031338	regulation of vesicle fusion
GO:0034613	cellular protein localization
GO:0042384	cilium assembly