Version 5.4
Homo sapiens Protein: BAG2
Summary
InnateDB Protein IDBP-91573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BAG2
Protein Name BCL2-associated athanogene 2
Synonyms BAG-2; dJ417I1.2;
Species Homo sapiens
Ensembl Protein ENSP00000359727
InnateDB Gene IDBG-91571 (BAG2)
Protein Structure
UniProt Annotation
Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 106 [view]
Protein-Protein 104 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0019538 protein metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003103 BAG domain
PFAM PF02179
PRINTS
PIRSF
SMART SM00264
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95816
PhosphoSite PhosphoSite-O95816
TrEMBL
UniProt Splice Variant
Entrez Gene 9532
UniGene Hs.743450
RefSeq NP_004273
HUGO HGNC:938
OMIM 603882
CCDS CCDS4961
HPRD 04859
IMGT
EMBL AF095192 AL031321 AL050287 AL136311 BC125039 CR533496
GenPept AAD16121 AAI25040 CAB43388 CAG38527 CAI20515 CAI21565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca