Version 5.4
Homo sapiens Protein: PPP1R26
Summary
InnateDB Protein IDBP-91911.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R26
Protein Name protein phosphatase 1, regulatory subunit 26
Synonyms KIAA0649;
Species Homo sapiens
Ensembl Protein ENSP00000349274
InnateDB Gene IDBG-91909 (PPP1R26)
Protein Structure
UniProt Annotation
Function Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. {ECO:0000269PubMed:16053918, ECO:0000269PubMed:19389623}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:16053918}.
Disease Associations
Tissue Specificity Ubiquitous in normal tissues. Expressed in numerous adenocarcinoma cell lines. {ECO:0000269PubMed:16053918}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5T8A7
PhosphoSite PhosphoSite-Q5T8A7
TrEMBL Q5T8A6
UniProt Splice Variant
Entrez Gene 9858
UniGene Hs.533260
RefSeq NP_055626
HUGO HGNC:29089
OMIM 614056
CCDS CCDS6988
HPRD 11099
IMGT
EMBL AB014549 AL161452 BC017511 BC047935
GenPept AAH17511 AAH47935 BAA31624 CAI14051

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca