InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CAMSAP1

Summary

InnateDB Protein

IDBP-92141.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CAMSAP1

Protein Name

calmodulin regulated spectrin-associated protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000312463

InnateDB Gene

IDBG-92139 (CAMSAP1)

Protein Structure

UniProt Annotation

Function

Probable microtubule-binding protein that plays a role in the regulation of cell morphology and cytoskeletal organization. Through interaction with spectrin may regulate neurite outgrowth. {ECO:0000269PubMed:19508979, ECO:0000269PubMed:21834987, ECO:0000269PubMed:24117850}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000269PubMed:19508979}. Note=Associates with microtubules.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0008017	microtubule binding
GO:0030507	spectrin binding

Biological Process

GO:0007010	cytoskeleton organization
GO:0022604	regulation of cell morphogenesis
GO:0031175	neuron projection development

Cellular Component

GO:0005737	cytoplasm
GO:0005874	microtubule

Protein Structure and Domains

PDB ID

InterPro

IPR001715 Calponin homology domain
IPR011033 PRC-barrel-like
IPR014797 CKK domain
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM

PF00307
PF08683
PF11971

PRINTS

PIRSF

SMART

SM00033
SM01051

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5T5Y3